Description

2-Pyrimidinamine, 4-Fluoro-6-Methyl- (9Ci) is a fluorinated pyrimidine derivative, a high-value chemical intermediate prized for its role in constructing complex molecular architectures. This compound matters for its utility in advanced pharmaceutical research and development, particularly in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce fluorine atoms for enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in antiviral, anticancer, and anti-inflammatory research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom improves efficacy and environmental profile.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Fluorinated Compound Production: Acts as a precursor for other complex fluorinated heterocycles used in material science and electronics.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-Pyrimidinamine, 4-Fluoro-6-Methyl- (9Ci)
CAS No.	18260-81-6
Molecular Formula	C5H6FN3
Molecular Weight	127.12 g/mol
Synonyms	4-Fluoro-6-methylpyrimidin-2-amine; 2-Amino-4-fluoro-6-methylpyrimidine; 4-Fluoro-6-methyl-2-pyrimidinamine; 6-Methyl-4-fluoropyrimidin-2-amine; 4-Fluoro-6-methyl-2-aminopyrimidine; 2-Pyrimidinamine, 4-fluoro-6-methyl-; 18260-81-6
EINECS	Contact for details

Quality Control

Our 2-Pyrimidinamine, 4-Fluoro-6-Methyl- (9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to reliable supply and traceability supports your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.