Description

2,6-Difluoro-5-Methylpyrimidin-4-Ylamine is a high-value fluorinated pyrimidine derivative, a key building block in advanced organic synthesis. Its molecular structure, featuring strategically placed fluorine atoms and an amine group, makes it a critical intermediate for creating compounds with enhanced biological activity and physicochemical properties. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral, anticancer, and kinase inhibitor drugs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms improve metabolic stability and bioavailability.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes and enzyme inhibitors for target identification and validation studies.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Item	Details
Product Name	2,6-Difluoro-5-Methylpyrimidin-4-Ylamine
CAS No.	18260-66-7
Molecular Formula	C5H5F2N3
Molecular Weight	145.11 g/mol
Synonyms	4-Amino-2,6-difluoro-5-methylpyrimidine; 5-Methyl-2,6-difluoropyrimidin-4-amine; 2,6-Difluoro-5-methyl-4-pyrimidinamine; 2,6-Difluoro-5-methylpyrimidin-4-amine; 4-Pyrimidinamine, 2,6-difluoro-5-methyl-
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-5-Methylpyrimidin-4-Ylamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.