Description

(Z)-1-(2,6-Difluorophenyl)Ethanone Oxime CAS NO 18184-17-3 is a high-purity, specialized oxime derivative characterized by its distinct difluorophenyl substitution pattern. This compound serves as a critical synthetic intermediate and building block in advanced organic synthesis, offering precise structural control for the development of novel molecules. It is primarily utilized by research institutions and industrial R&D departments within the pharmaceutical and agrochemical sectors, where its unique fluorinated scaffold is leveraged to modulate the biological activity and physicochemical properties of target compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the difluorophenyl group can enhance metabolic stability and bioavailability.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs), exploiting the oxime functional group's chelating properties.
• Chemical Biology Probes: Acts as a precursor for creating molecular probes to study enzyme function or biological pathways in research settings.
• Material Science: Investigated as a monomer or cross-linking agent for the development of novel polymers with specific thermal or chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-directed custom synthesis projects.

Basic Information

Product Name	(Z)-1-(2,6-Difluorophenyl)Ethanone Oxime
CAS No.	18184-17-3
Molecular Formula	C8H7F2NO
Molecular Weight	171.15 g/mol
Synonyms	1-(2,6-Difluorophenyl)ethanone oxime; (Z)-2,6-Difluoroacetophenone oxime; α-(2,6-Difluorophenyl)ethanone oxime; 2',6'-Difluoroacetophenone oxime; (Z)-1-(2,6-Difluorophenyl)ethan-1-one oxime; Acetophenone, 2',6'-difluoro-, oxime; Ethanone, 1-(2,6-difluorophenyl)-, oxime
EINECS	Contact for details

Quality Control

Our (Z)-1-(2,6-Difluorophenyl)Ethanone Oxime is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing specifications such as assay (by HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.