Description

4-Methoxy-2-Nitrobenzenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, primarily used as a key synthetic intermediate in advanced organic synthesis. Its value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl group to construct complex molecules with precision. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs), dyes, and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, especially sulfonamide-based therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides that require specific sulfonyl functional groups.
• Dye and Pigment Manufacturing: Serves as a precursor for synthesizing azo dyes and other colored compounds with enhanced properties.
• Polymer Chemistry: Employed in the modification of polymers and the creation of specialty monomers to impart specific chemical functionalities.
• Peptide and Protein Research: Acts as a protecting group reagent or a coupling agent in peptide synthesis and biochemical studies.
• Material Science: Utilized in the development of advanced materials, including liquid crystals and organic semiconductors.

Basic Information

Product Name	4-Methoxy-2-Nitrobenzenesulfonyl Chloride
CAS No.	18092-54-1
Molecular Formula	C7H6ClNO5S
Molecular Weight	251.64 g/mol
Synonyms	2-Nitro-4-methoxybenzenesulfonyl chloride; 4-Methoxy-2-nitrobenzenesulfonyl chloride; 1-Methoxy-4-nitro-2-sulfonylchloridobenzene; 2-Nitroanisole-4-sulfonyl chloride; 4-Methoxy-2-nitrobenzene-1-sulfonyl chloride; NSC 403107; p-Methoxy-o-nitrobenzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methoxy-2-Nitrobenzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and FTIR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.