Description

H-Gly-Ala-Phe-Oh CAS NO 17922-87-1 is a synthetic tripeptide composed of glycine, alanine, and phenylalanine residues, serving as a crucial building block and research tool in peptide chemistry. Its defined sequence and high purity make it essential for developing novel bioactive compounds and studying peptide structure-activity relationships. This product is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions engaged in peptide synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: Used as a key starting material or fragment in the solid-phase and solution-phase synthesis of more complex therapeutic peptides.
• Biochemical Research: Serves as a standard or substrate in enzymatic studies, proteomics research, and investigations into peptide metabolism and transport.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the biological activity and pharmacokinetic properties of peptide-based drug candidates.
• Cosmetic Peptide Synthesis: Acts as a precursor for synthesizing peptides used in cosmetic formulations targeting skin conditioning and anti-aging.
• Academic & Teaching Tool: Utilized in university laboratories for teaching advanced peptide synthesis techniques and principles of amino acid coupling.

Basic Information

Product Name	H-Gly-Ala-Phe-Oh
CAS No.	17922-87-1
Molecular Formula	C₁₄H₁₉N₃O₄
Molecular Weight	293.32 g/mol
Synonyms	Glycyl-alanyl-phenylalanine; GAF-OH; H-Gly-Ala-Phe-OH; Tripeptide GAF; Gly-Ala-Phe; 2-[[2-[(2-Aminoacetyl)amino]propanoyl]amino]-3-phenylpropanoic acid; N-Glycyl-L-alanyl-L-phenylalanine
EINECS	Contact for details

Quality Control

Our H-Gly-Ala-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.