Description

5-Bromo-2-Ethoxy-Pyrimidine is a versatile halogenated pyrimidine derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in its dual functionality, where the bromine atom serves as an excellent site for cross-coupling reactions, and the ethoxy group can act as a directing or protecting group. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for developing active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of nucleoside analogs, kinase inhibitors, and other small molecule APIs targeting various therapeutic areas.
• Agrochemical Development: Used in constructing pyrimidine-based herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or molecular components for conductive polymers.
• Cross-Coupling Reactions: The bromine substituent makes it an ideal substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions to create complex biaryl structures.
• Chemical Biology & Proteomics: Can be utilized as a tagged building block for creating chemical probes or affinity labels to study biological systems.
• Academic & Contract Research: A valuable reagent for methodology development and discovery chemistry in research laboratories.

Basic Information

Product Name	5-Bromo-2-Ethoxy-Pyrimidine
CAS No.	17758-11-1
Molecular Formula	C6H7BrN2O
Molecular Weight	203.04 g/mol
Synonyms	2-Ethoxy-5-bromopyrimidine; 5-Bromo-2-ethoxypyrimidine; Pyrimidine, 5-bromo-2-ethoxy-; 5-Brom-2-aethoxy-pyrimidin (German); 5-Bromo-2-ethoxy-1,3-diazine
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Ethoxy-Pyrimidine is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and lot-to-lot consistency suitable for demanding R&D and scale-up processes. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.