Description

L-Isoleucine Hydrochloride is the hydrochloride salt form of the essential branched-chain amino acid L-Isoleucine. This high-purity compound is critical for applications demanding precise biochemical activity and consistent quality. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and research sectors for its role in protein synthesis and metabolic functions.

Application

• Pharmaceutical Intermediates: Used in the synthesis of active pharmaceutical ingredients (APIs) and parenteral nutrition formulations.
• Cell Culture Media: An essential nutrient component in mammalian and microbial cell culture systems for biopharmaceutical production.
• Dietary Supplements & Sports Nutrition: Incorporated into amino acid blends, protein powders, and clinical nutrition products to support muscle protein synthesis.
• Biochemical Research: Serves as a standard and reagent in enzymatic studies, metabolic pathway analysis, and microbiological assays.
• Diagnostic Reagents: Used in the formulation of kits and solutions for clinical diagnostics and analytical testing.

Basic Information

Product Name	L-Isoleucine Hydrochloride
CAS No.	17694-98-3
Molecular Formula	C6H13NO2·HCl
Molecular Weight	167.63 g/mol
Synonyms	(2S,3S)-2-Amino-3-methylpentanoic acid hydrochloride; L-Ile HCl; (S)-Isoleucine hydrochloride; Isoleucine HCl; L-(-)-Isoleucine hydrochloride; L-α-Amino-β-methylvaleric acid hydrochloride; (2S,3S)-Isoleucine hydrochloride
EINECS	241-692-4

Quality Control

Our L-Isoleucine Hydrochloride is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets stringent purity and identity criteria. We can supply material compliant with various pharmacopeial standards, including USP and EP. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Specific Rotation	+38.0° to +41.0° (c=4 in 6N HCl)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Chloride Content (Titration)	19.0% - 21.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.