Description

5-Nitroorotic Acid is a specialized nitro-substituted derivative of orotic acid, a key intermediate in nucleotide biosynthesis. This compound is valued for its role as a versatile building block in organic synthesis and pharmaceutical research, particularly in the development of novel heterocyclic compounds. It serves the needs of research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in advanced synthetic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting nucleotide metabolism pathways.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to pyrimidine biosynthesis and metabolism.
• Organic Synthesis Building Block: Utilized in the construction of complex heterocyclic frameworks due to its reactive nitro and carboxylic acid functional groups.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Material Science Research: Investigated for the development of novel organic materials and ligands for metal coordination complexes.

Basic Information

Item	Detail
Product Name	5-Nitroorotic Acid
CAS No.	17687-24-0
Molecular Formula	C5H3N3O6
Molecular Weight	201.10 g/mol
Synonyms	5-Nitro-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid; 5-Nitro-1H-pyrimidine-2,6-dione-4-carboxylic acid; 5-Nitroorotic acid monohydrate; 5-Nitrobarbituric acid-4-carboxylic acid; 4-Carboxy-5-nitrouracil; NSC 403697; 5-NO2-OA
EINECS	Contact for details

Quality Control

Our 5-Nitroorotic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and development use. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Yellow to pale brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.