Description

H-Leu-D-Leu-Oh CAS NO 17665-02-0 is a high-purity dipeptide derivative, specifically the D-isomer of the leucine-leucine dipeptide, valued for its role as a critical chiral building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring precise stereochemical control in the development of complex molecules. It finds significant utility in the pharmaceutical industry for peptide-based drug discovery and in biochemical research for studying enzyme specificity and protein folding.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for probing the mechanisms of proteases and other enzymes.
• Peptide Synthesis: Serves as a protected dipeptide unit in solid-phase and solution-phase peptide synthesis for constructing longer, more complex peptide chains.
• Asymmetric Synthesis: Employed as a chiral auxiliary or building block to induce stereoselectivity in organic reactions.
• Reference Standard: Utilized as an analytical standard in chromatography (HPLC, LC-MS) for method development and quality control of related peptide products.

Basic Information

Product Name	H-Leu-D-Leu-Oh
CAS No.	17665-02-0
Molecular Formula	C12H24N2O3
Molecular Weight	244.33 g/mol
Synonyms	L-Leucyl-D-leucine; D-Leu-L-Leu-OH; (2R)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]-4-methylpentanoic acid; H-L-Leu-D-Leu-OH; Leu-D-Leu; Leucine-D-leucine dipeptide; D-Leu-L-Leu; N-(L-Leucyl)-D-leucine
EINECS	Contact for details

Quality Control

Our H-Leu-D-Leu-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles. We support research and development with material that meets stringent in-house specifications, suitable for demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which may affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.