Description

L-Leu-D-Val-Oh is a high-purity dipeptide building block, specifically the L-leucyl-D-valine derivative. This compound is essential for advanced peptide synthesis, offering precise stereochemical control for creating complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and biochemical tools.

Application

• Pharmaceutical Intermediate: A critical building block for the solid-phase and solution-phase synthesis of therapeutic peptides targeting various diseases.
• Biochemical Research: Used in proteomics and enzymology studies as a substrate or inhibitor analog to investigate enzyme mechanisms.
• Peptidomimetic Development: Serves as a core structural element in the design of metabolically stable peptide mimics with enhanced drug-like properties.
• Cosmetic Peptide Synthesis: Incorporated into bioactive peptides for skincare formulations aimed at anti-aging or skin repair.
• Academic & R&D Laboratories: Employed in chemical biology and medicinal chemistry research for constructing custom peptide libraries.

Basic Information

Product Name	L-Leu-D-Val-Oh
CAS No.	17665-00-8
Molecular Formula	C11H22N2O3
Molecular Weight	230.31 g/mol
Synonyms	L-Leucyl-D-valine; (2S)-2-[[(2R)-2-Amino-3-methylbutanoyl]amino]-4-methylpentanoic acid; H-Leu-Val-OH; Leu-Val; L-Leu-D-Val; D-Val-L-Leu-OH; N-(L-Leucyl)-D-valine; D-Valine, N-L-leucyl-
EINECS	Contact for details

Quality Control

Our L-Leu-D-Val-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and identity confirmation via IR and MS. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Specific range provided on COA
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.