Description

H-Leu-D-Ala-Oh CAS NO 17664-98-1 is a high-purity, synthetic dipeptide derivative featuring a D-alanine residue. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel peptide-based therapeutics and bioactive compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new peptide drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or building block in enzymatic studies, metabolic pathway investigations, and proteomics research.
• Peptide Synthesis: An essential component in solid-phase and solution-phase peptide synthesis (SPPS) for constructing complex peptide sequences.
• Protease & Enzyme Studies: Employed in studying enzyme specificity, inhibition, and kinetics, particularly for proteases that recognize leucine and alanine motifs.
• Fine Chemical Production: Acts as a specialized intermediate in the synthesis of complex organic molecules, flavors, and fragrances.
• Academic & Industrial R&D: Serves as a standard or reagent in method development and analytical chemistry within life science laboratories.

Basic Information

Product Name	H-Leu-D-Ala-Oh
CAS No.	17664-98-1
Molecular Formula	C9H18N2O3
Molecular Weight	202.25 g/mol
Synonyms	L-Leucyl-D-alanine; D-Alanine, L-leucyl-; H-Leu-D-Ala-OH; Leucyl-D-alanine; (2R)-2-[[(2S)-2-amino-4-methylpentanoyl]amino]propanoic acid; L-Leu-D-Ala; N-L-Leucyl-D-alanine; D-Ala-L-Leu-OH
EINECS	Contact for details

Quality Control

Every batch of H-Leu-D-Ala-Oh is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (D-Ala)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.