Description

Caerulein is a synthetic decapeptide analog of the natural peptide hormone cholecystokinin (CCK). This compound is a potent and selective agonist for CCK receptors, making it a critical research tool in neurobiology, gastroenterology, and pharmacology. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies. Caerulein CAS NO 17650-98-5 is valued for its ability to reliably stimulate pancreatic secretion and induce experimental pancreatitis models.

Application

• Pharmacological Research: As a standard CCK receptor agonist for studying receptor function, signal transduction pathways, and drug mechanisms of action.
• Gastrointestinal Studies: Used to investigate pancreatic exocrine secretion, gallbladder contraction, and gut motility in experimental models.
• Neuroscience Research: Employed in studies related to satiety, anxiety, pain perception, and memory, where CCK pathways are involved.
• Disease Modeling: Induction of acute experimental pancreatitis in animal models for pathophysiological and therapeutic intervention studies.
• Biochemical Assay Development: Serves as a reference standard in the development and validation of bioanalytical methods (e.g., ELISA, HPLC).
• Peptide Chemistry Reference: Used as a model compound in peptide synthesis, purification, and analytical technique development.

Basic Information

Product Name	Caerulein
CAS No.	17650-98-5
Molecular Formula	C58H73N13O21S2
Molecular Weight	1352.4 g/mol
Synonyms	Ceruletide; Cerulein; Caerulein diethylamine; FI 6934; SQ 19844; pGlu-Gln-Asp-Tyr(SO3H)-Thr-Gly-Trp-Met-Asp-Phe-NH2; Cholecystokinin decapeptide; CCK-10
EINECS	Contact for details

Quality Control

Our Caerulein is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity and identity confirmation, amino acid analysis, and mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing assay results, impurity profiles, and physical characteristics to ensure compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.