Description

n-Acetyl-3-Fluoro-Dl-Phenylalanine is a fluorinated and acetylated derivative of the amino acid phenylalanine, serving as a versatile chiral building block and synthetic intermediate. This compound is valued for its role in modulating the biological and physicochemical properties of peptides and other bioactive molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for drug discovery, peptide synthesis, and the development of novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates.
• Peptide Chemistry: Used in solid-phase and solution-phase peptide synthesis to incorporate fluorinated phenylalanine analogs, potentially enhancing metabolic stability and bioavailability.
• Proteomics & Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies and as a tool compound for investigating protein structure-function relationships.
• Agrochemical Development: Employed in the synthesis of advanced fluorinated pesticides and herbicides, leveraging the fluorine atom's ability to influence lipophilicity and biological activity.
• Material Science: Acts as a precursor for specialty polymers and advanced materials where fluorinated aromatic groups are required for specific performance characteristics.

Basic Information

Product Name	n-Acetyl-3-Fluoro-Dl-Phenylalanine
CAS No.	17607-28-2
Molecular Formula	C11H12FNO3
Molecular Weight	225.22 g/mol
Synonyms	N-Acetyl-3-fluoro-DL-phenylalanine; 3-Fluoro-N-acetyl-DL-phenylalanine; DL-3-Fluoro-N-acetylphenylalanine; Ac-3-F-DL-Phe-OH; N-Acetyl-3-fluorophenylalanine; (±)-N-Acetyl-3-fluorophenylalanine; 2-Acetamido-3-(3-fluorophenyl)propanoic acid; NSC 334905
EINECS	Contact for details

Quality Control

Our n-Acetyl-3-Fluoro-Dl-Phenylalanine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR). We provide full traceability and Certificates of Analysis (COA) are available for all shipments to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (DL Ratio)	~50:50 (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.