Description

N,n-Dimethyl-o-Glucopyranuronosyl-5-Hydroxytryptamine is a chemically modified derivative of serotonin, where the indoleamine is conjugated with a glucuronic acid moiety. This structural modification is significant as it can alter the compound's bioavailability, metabolic pathway, and receptor interaction profile, making it a valuable intermediate for advanced pharmaceutical research. It is primarily needed by research institutions and pharmaceutical companies engaged in neurochemistry, drug metabolism studies, and the development of novel therapeutic agents targeting serotonin-related pathways.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor or metabolite analog in the development of central nervous system (CNS) drugs.
• Biochemical Research: Used as a reference standard or probe in studies investigating serotonin conjugation, transport, and receptor binding mechanisms.
• Metabolite Synthesis: Critical for the synthesis of glucuronidated metabolites for pharmacokinetic and pharmacodynamic (PK/PD) modeling.
• Neuroscience Studies: Applied in vitro and in vivo to explore the role of serotonin derivatives in neurological functions and disorders.
• Analytical Standard: Employed as a high-purity calibrant in advanced analytical techniques like LC-MS/MS for bioanalysis.

Basic Information

Product Name	N,n-Dimethyl-o-Glucopyranuronosyl-5-Hydroxytryptamine
CAS No.	17598-73-1
Molecular Formula	C19H26N2O8
Molecular Weight	410.42 g/mol
Synonyms	5-Hydroxytryptamine N,N-dimethylglucuronide; Serotonin glucuronide dimethyl derivative; N,N-Dimethylserotonin glucuronide; O-Glucuronosyl-N,N-dimethyl-5-hydroxytryptamine; 5-HT-O-glucuronide dimethylated; N,N-Dimethyl-5-hydroxytryptamine-O-β-D-glucopyranosiduronic acid
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-o-Glucopyranuronosyl-5-Hydroxytryptamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.