Description

8-Chloropurine is a halogenated purine derivative, a crucial heterocyclic building block in organic synthesis. Its primary value lies in serving as a versatile intermediate for the development of nucleoside analogs and other biologically active compounds. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and life science industries, where precise molecular modification is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of antiviral and anticancer nucleoside drugs, such as acyclovir and ganciclovir analogs.
• Agrochemical Research: Used as a building block for developing novel pesticides and plant growth regulators that target specific biological pathways.
• Biochemical Tool Compound: Employed in life science research to study enzyme inhibition, nucleotide metabolism, and purinergic signaling pathways.
• Nucleic Acid Chemistry: Serves as a modified base for oligonucleotide synthesis, enabling the creation of probes and therapeutic agents with altered properties.
• Chemical Synthesis: A versatile starting material for further functionalization to create a library of purine-based compounds for screening and development.

Basic Information

Product Name	8-Chloropurine
CAS No.	17587-87-0
Molecular Formula	C5H3ClN4
Molecular Weight	154.56 g/mol
Synonyms	8-Chloro-7H-purine; 8-Chloro-9H-purine; Purine, 8-chloro-; 8-Chlor-7H-purine; 8-Cl-Purine; NSC 74685; 8-Chloropurine (principal name)
EINECS	Contact for details

Quality Control

Our 8-Chloropurine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.