Description

6-Bromo-7-chloroquinazolin-4-ol is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. This compound is valued for its role as a key precursor in the development of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel quinazoline-based compounds.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of tyrosine kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides and fungicides based on the quinazoline scaffold.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and hit-to-lead optimization.
• Organic Synthesis Building Block: Utilized in palladium-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to introduce complex functionality.
• Material Science Research: Investigated as a potential monomer or dopant for creating organic electronic materials with specific optoelectronic properties.

Basic Information

Product Name	6-Bromo-7-chloroquinazolin-4-ol
CAS No.	17518-95-5
Molecular Formula	C8H4BrClN2O
Molecular Weight	259.49 g/mol
Synonyms	4-Hydroxy-6-bromo-7-chloroquinazoline; 6-Bromo-7-chloro-4-quinazolinol; 6-Bromo-7-chloro-4-hydroxyquinazoline; 7-Chloro-6-bromoquinazolin-4-ol; 17518-95-5; Quinazolin-4-ol, 6-bromo-7-chloro-; 6-Bromo-7-chloro-4(3H)-quinazolinone
EINECS	Contact for details

Quality Control

Our 6-Bromo-7-chloroquinazolin-4-ol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles for pharmaceutical-grade intermediates, ensuring compliance with global regulatory expectations for advanced synthetic building blocks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.