Description

3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-11β,14-Dihydroxy-5α-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a critical intermediate in advanced pharmaceutical synthesis. Its value lies in its specific stereochemistry and functional groups, which are essential for developing potent and selective therapeutic agents. This compound is primarily needed by research institutions and pharmaceutical manufacturers focused on cardiovascular drug discovery and the production of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel cardiac glycoside-based therapeutics.
• Cardiovascular Research: Used as a reference standard and precursor in biochemical studies targeting sodium-potassium ATPase.
• API Development: Serves as a crucial intermediate in the multi-step synthesis of complex, high-potency active pharmaceutical ingredients.
• Medicinal Chemistry: Provides a sophisticated scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Assays: Employed as a ligand or inhibitor in enzymatic and receptor-binding assays to study cardiac function.
• Standards and Calibrants: Used to prepare analytical standards for quality control and regulatory testing in pharmaceutical manufacturing.

Basic Information

Product Name	3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-11β,14-Dihydroxy-5α-Card-20(22)-Enolide
CAS No.	17489-40-6
Molecular Formula	C29H44O9
Molecular Weight	536.66 g/mol
Synonyms	Digitoxigenin 6-deoxy-α-L-mannoside; 3β-[(6-Deoxy-α-L-mannopyranosyl)oxy]-11β,14-dihydroxy-5α-card-20(22)-enolide; 6'-Deoxy-α-L-mannosyldigitoxigenin; 11β,14-Dihydroxy-3β-[(6-deoxy-α-L-mannopyranosyl)oxy]-5α-card-20(22)-enolide; Strophanthidin α-L-rhamnoside; α-L-Rhamnosylstrophanthidin; (3β,5α,11β)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-11,14-dihydroxycard-20(22)-enolide
EINECS	Contact for details

Quality Control

Our 3β-[(6-Deoxy-α-L-Mannopyranosyl)Oxy]-11β,14-Dihydroxy-5α-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.