Description

L-5-Hydroxytryptophan Hydrochloride is a high-purity, pharmaceutically relevant salt form of the essential amino acid precursor 5-HTP. This compound serves as a critical direct precursor in the biosynthesis of the neurotransmitter serotonin, making it a valuable intermediate for research and development. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and advanced biochemical research sectors for the production of active pharmaceutical ingredients (APIs), dietary supplements, and as a key reference standard.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of serotonergic agents and other neuroactive pharmaceutical compounds.
• Dietary Supplement Formulation: Used as the active ingredient in capsules and tablets aimed at supporting mood, sleep, and cognitive function.
• Biochemical Research: Employed as a standard and reagent in neuroscience, pharmacology, and metabolic pathway studies.
• Reference Standard: Serves as a high-purity calibrant in analytical laboratories for quality control testing via HPLC, LC-MS, and other methods.
• Precursor for Further Chemical Synthesis: Used in organic synthesis to create more complex molecules for medicinal chemistry applications.

Basic Information

Product Name	L-5-Hydroxytryptophan Hydrochloride
CAS No.	17469-40-8
Molecular Formula	C11H12N2O3 • HCl
Molecular Weight	256.68 g/mol
Synonyms	5-HTP HCl; L-5-HTP Hydrochloride; (S)-5-Hydroxytryptophan Hydrochloride; 5-Hydroxy-L-tryptophan Hydrochloride; Oxitriptan Hydrochloride; Levotonine Hydrochloride; 3-(5-Hydroxy-1H-indol-3-yl)-L-alanine Hydrochloride
EINECS	Contact for details

Quality Control

Our L-5-Hydroxytryptophan Hydrochloride is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling to ensure it meets stringent specifications for pharmaceutical and research use. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Optical Rotation	-30° to -34° (c=1 in H2O)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.