Description

2,2,2-Trifluoro-1-(2-Nitrophenyl)Ethanone is a specialized fluorinated aromatic ketone building block, distinguished by its trifluoromethyl and ortho-nitro substituents. This compound is valued for its unique electronic properties and reactivity, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for constructing complex molecules, including active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and advanced organic electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and as a substrate for the introduction of the 2-nitrophenyl moiety into complex molecular architectures.
• Chemical Research & Development: Utilized in academic and industrial R&D labs for method development and exploring new reaction pathways involving fluorinated aromatics.

Basic Information

Product Name	2,2,2-Trifluoro-1-(2-Nitrophenyl)Ethanone
CAS No.	17408-17-2
Molecular Formula	C8H4F3NO3
Molecular Weight	219.12 g/mol
Synonyms	2-Nitro-α,α,α-trifluoroacetophenone; 2,2,2-Trifluoro-1-(2-nitrophenyl)ethan-1-one; 1-(2-Nitrophenyl)-2,2,2-trifluoroethanone; α,α,α-Trifluoro-2-nitroacetophenone; 2-Nitro-α,α,α-trifluoroacetophenone; o-Nitro-α,α,α-trifluoroacetophenone; 2-Nitrophenyl trifluoromethyl ketone
EINECS	Contact for details

Quality Control

Our 2,2,2-Trifluoro-1-(2-Nitrophenyl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of advanced organic synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.