Description

Z-Trp-Ala-Oh is a high-purity, protected dipeptide building block widely used in advanced peptide synthesis. This compound is essential for researchers and manufacturers requiring precise control over peptide chain assembly, particularly for introducing the tryptophan and alanine residues. It serves as a critical intermediate for pharmaceutical R&D, enabling the creation of novel therapeutic peptides and biochemical probes. Its consistent quality and stability make it a reliable choice for demanding applications in drug discovery and development.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the sequential construction of complex peptide sequences.
• Pharmaceutical Research: Used in the discovery and development of new peptide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Bioconjugation: Serves as a building block for creating peptide tags, linkers, and modified biomolecules.
• Biochemical Research: Employed in studying enzyme-substrate interactions, receptor binding, and other structure-activity relationship (SAR) studies.
• Custom Peptide Manufacturing: A fundamental raw material for CROs and CDMOs producing bespoke peptides for clients.
• Proteomics: Can be utilized in the synthesis of standardized peptides for mass spectrometry calibration and analytical methods.

Basic Information

Product Name	Z-Trp-Ala-Oh
CAS No.	17388-71-5
Molecular Formula	C24H25N3O5
Molecular Weight	435.48 g/mol
Synonyms	N-[(Benzyloxy)carbonyl]-L-tryptophyl-L-alanine; Z-L-Tryptophyl-L-alanine; Z-L-Trp-L-Ala-OH; N-Cbz-L-Tryptophyl-L-alanine; CBZ-L-Tryptophyl-L-alanine; N-Carbobenzoxy-L-tryptophyl-L-alanine; (S)-2-(((S)-1-((Benzyloxy)carbonyl)-2-(1H-indol-3-yl)ethyl)amino)-1-oxopropan-1-ium-1-olate; Z-Tryptophan-Alanine
EINECS	Contact for details

Quality Control

Our Z-Trp-Ala-Oh is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes. We support compliance with relevant guidelines for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.