Description

Z-Trp-Gly-Oh is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of Tryptophylglycine. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), offering controlled reactivity and protecting sensitive functional groups during complex peptide assembly. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors developing novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled, sequential construction of longer peptide chains.
• Pharmaceutical Research: Used in the development and production of peptide drugs, hormones, and enzyme inhibitors.
• Bioconjugation: Acts as a linker or spacer molecule in the creation of peptide-protein or peptide-small molecule conjugates.
• Biochemical Tool Development: Employed in synthesizing substrates, inhibitors, or standards for enzymatic assays and diagnostic kits.
• Academic & Industrial R&D: Fundamental reagent for exploring peptide structure-activity relationships (SAR) and new synthetic methodologies.

Basic Information

Product Name	Z-Trp-Gly-Oh
CAS No.	17388-70-4
Molecular Formula	C21H21N3O5
Molecular Weight	395.41 g/mol
Synonyms	N-Carbobenzyloxy-L-tryptophylglycine; N-Cbz-L-tryptophylglycine; Z-L-Tryptophylglycine; Z-L-Trp-Gly-OH; Nα-Cbz-L-Tryptophylglycine; Benzyloxycarbonyl-L-tryptophylglycine; CBZ-Tryptophan-Glycine; N-CBZ-L-Tryptophan-Glycine
EINECS	Contact for details

Quality Control

Our Z-Trp-Gly-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from HPLC, NMR, and MS, supporting compliance with cGMP guidelines for pharmaceutical intermediates. Specifications are designed to meet the rigorous demands of research and commercial peptide synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Optical Rotation	-20° to -25° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.