Description

1-(4-Fluorophenyl)Cyclohexan-1-Amine is a versatile fluorinated amine building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cyclohexylamine core substituted with a fluorinated aromatic ring, makes it a critical intermediate for developing novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries seeking to incorporate fluorinated motifs into their molecular designs.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disorder therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials with tailored properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent dyes, biomarkers, and other diagnostic reagents.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs for the production of complex, high-value target molecules on a commercial scale.

Basic Information

Product Name	1-(4-Fluorophenyl)Cyclohexan-1-Amine
CAS No.	17380-80-2
Molecular Formula	C12H16FN
Molecular Weight	193.26 g/mol
Synonyms	4-Fluoro-α-cyclohexylbenzenemethanamine; 1-(4-Fluorophenyl)cyclohexylamine; 4-Fluorophenylcyclohexylamine; 1-Amino-1-(4-fluorophenyl)cyclohexane; 1-Cyclohexyl-1-(4-fluorophenyl)amine; 4-Fluoro-α-cyclohexylbenzylamine; p-Fluorophenylcyclohexylamine; 1-(p-Fluorophenyl)cyclohexanamine
EINECS	Contact for details

Quality Control

Our production of 1-(4-Fluorophenyl)Cyclohexan-1-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor quality specifications to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong acids, and moisture. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.