Description

1-Palmitoyl-Sn-Glycero-3-Phosphocholine is a high-purity synthetic phospholipid, specifically a lysophosphatidylcholine (LPC), that serves as a critical building block and reference standard in advanced life science research and pharmaceutical development. Its defined structure is essential for studying membrane biophysics, lipid metabolism, and cell signaling pathways. This compound is particularly valuable for researchers and formulators in the pharmaceutical, biotechnology, and nutraceutical industries, where precise lipid composition is paramount for creating liposomal drug delivery systems, diagnostic assays, and cellular models.

Application

• Liposomal Drug Delivery Systems: A key component for formulating stable liposomes and lipid nanoparticles (LNPs) used to encapsulate and deliver therapeutic agents, including mRNA vaccines and cancer drugs.
• Biochemical & Biomedical Research: Employed as a critical reagent and standard in studies of phospholipase activity, lipid signaling, membrane fusion, and cell membrane dynamics.
• Cell Culture & Media Supplement: Used as a surfactant or lipid source in specialized cell culture media to support the growth of certain cell types.
• Diagnostic Assay Development: Acts as a substrate or coating agent in enzymatic assays and diagnostic kits for detecting specific phospholipases or other lipid-related biomarkers.
• Pharmaceutical Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical manufacturing.
• Biophysical Studies: Utilized in model membrane systems (e.g., vesicles, monolayers) to investigate lipid-protein interactions and membrane permeability.

Basic Information

Product Name	1-Palmitoyl-Sn-Glycero-3-Phosphocholine
CAS No.	17364-16-8
Molecular Formula	C24H50NO7P
Molecular Weight	495.63 g/mol
Synonyms	LPC (16:0); 1-Hexadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine; LysoPC(16:0); Palmitoyl Lysophosphatidylcholine; 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphocholine; sn-Glycero-3-phosphocholine, 1-palmitoyl-; Lysophosphatidylcholine 16:0; Lysolectihin 16:0
EINECS	241-403-5

Quality Control

Our 1-Palmitoyl-Sn-Glycero-3-Phosphocholine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to minimize oxidation. Due to its hygroscopic nature, the container should be allowed to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or waxy solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Solubility	Soluble in chloroform, methanol; slightly soluble in water
Loss on Drying	≤ 2.0 %
Heavy Metals	≤ 10 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.