Description

H-Tyr-Val-Oh is a high-purity dipeptide building block, specifically L-Tyrosyl-L-valine, essential for advanced peptide synthesis and pharmaceutical research. Its value lies in providing a precisely defined molecular fragment for constructing complex bioactive peptides and peptidomimetics, ensuring consistent quality and performance in downstream applications. This compound is primarily needed by research institutions, pharmaceutical developers, and fine chemical manufacturers engaged in drug discovery, proteomics, and the production of specialized peptide-based active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Critical building block for the solid-phase and solution-phase synthesis of therapeutic peptides targeting metabolic disorders, neurological conditions, and hormonal therapies.
• Biochemical Research: Used as a standard or substrate in enzymatic studies, proteomics research, and investigations into peptide structure-activity relationships (SAR).
• Peptide Library Construction: A key component in combinatorial chemistry for generating diverse peptide libraries used in high-throughput screening for drug lead identification.
• Cosmeceutical Ingredient Synthesis: Serves as a precursor for synthesizing bioactive peptide sequences used in advanced skincare and anti-aging formulations.
• Academic & Industrial R&D: Fundamental reagent for universities and corporate R&D departments exploring novel peptide conjugates, drug delivery systems, and biomaterials.

Basic Information

Product Name	H-Tyr-Val-Oh
CAS No.	17355-09-8
Molecular Formula	C₁₄H₂₀N₂O₄
Molecular Weight	280.32 g/mol
Synonyms	L-Tyrosyl-L-valine; Tyr-Val; TYV; H-L-Tyr-L-Val-OH; N-(N-L-Tyrosyl)-L-valine; L-Valine, L-tyrosyl-; (2S)-2-[[(2S)-2-Amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoic acid; L-Tyrosine-L-valine
EINECS	Contact for details

Quality Control

Our H-Tyr-Val-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, typically meeting standards suitable for pharmaceutical research. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines, and specifications can be tailored to meet specific project requirements for advanced R&D and GMP-grade applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	[α]²⁰D: Specific range available on COA
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.