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N6-Acetyl-N2-[n-(n-Acetyl-L-Alanyl)-L-Alanyl]-L-Lysine Methyl Ester CAS NO 17353-67-2


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CAS No.:17353-67-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

N6-Acetyl-N2-[n-(n-Acetyl-L-Alanyl)-L-Alanyl]-L-Lysine Methyl Ester is a specialized, high-purity peptide derivative used as a critical building block in advanced chemical synthesis. This compound matters for its role as a protected lysine derivative, enabling precise peptide chain assembly and modification in complex research and development workflows. It is primarily needed by pharmaceutical R&D teams, biotechnology companies, and academic laboratories focused on peptide-based drug discovery, proteomics, and biochemical studies.

Application

  • Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
  • Biochemical Research: Used as a substrate or reference standard in enzymatic studies, proteomics research, and investigations into post-translational modifications.
  • Peptide Synthesis: Functions as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis (SPPS), facilitating the construction of complex peptide sequences.
  • Protease & Enzyme Studies: Employed in the study of enzyme kinetics and specificity, particularly for proteases that recognize lysine or acetylated lysine residues.
  • Chemical Biology Probes: Utilized in the design and synthesis of chemical probes for studying protein-protein interactions and cellular signaling pathways.
  • Reference Standard: Acts as a high-purity analytical standard for quality control and method development in chromatographic analysis (HPLC, LC-MS).

Basic Information

Product Name N6-Acetyl-N2-[n-(n-Acetyl-L-Alanyl)-L-Alanyl]-L-Lysine Methyl Ester
CAS No. 17353-67-2
Molecular Formula C19H32N4O7
Molecular Weight 428.48 g/mol
Synonyms Ac-Lys(Ac)-Ala-Ala-OMe; Nε-Acetyl-Nα-(N-acetyl-L-alanyl-L-alanyl)-L-lysine Methyl Ester; Acetyl-Lys(Acetyl)-Ala-Ala Methyl Ester; L-Lysine, N6-acetyl-N2-[N-(N-acetyl-L-alanyl)-L-alanyl]-, methyl ester; Methyl Nε-acetyl-Nα-(N-acetyl-L-alanyl-L-alanyl)-L-lysinate; Ac-Lys(Ac)-AA-OMe; N-Acetyl-L-alanyl-Nα-(Nε-acetyl-L-lysyl)-L-alanine methyl ester
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Quality Control

Our N6-Acetyl-N2-[n-(n-Acetyl-L-Alanyl)-L-Alanyl]-L-Lysine Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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