Description

H-Met-Ala-Ser-Oh CAS NO 17351-33-6 is a protected tripeptide derivative, specifically the methyl ester of the sequence H-Met-Ala-Ser. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled assembly of larger, complex peptide chains. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, diagnostic agents, and biochemical tools.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the sequential construction of custom peptide sequences in pharmaceutical and biochemical research.
• Pharmaceutical Intermediate: Used in the research and development of potential therapeutic peptides targeting various metabolic and signaling pathways.
• Bioconjugation & Labeling Studies: The reactive side chains (when deprotected) allow for site-specific modifications, useful in creating peptide-drug conjugates or fluorescent probes.
• Biochemical Research: Employed in studies of enzyme-substrate interactions, protein folding, and as a standard in analytical method development for peptide characterization.
• Combinatorial Chemistry Libraries: Serves as a key component in generating diverse peptide libraries for high-throughput screening in drug discovery.

Basic Information

Item	Detail
Product Name	H-Met-Ala-Ser-Oh
CAS No.	17351-33-6
Molecular Formula	C12H21N3O5S
Molecular Weight	319.38 g/mol
Synonyms	H-Met-Ala-Ser-OMe; Methionylalanylserine methyl ester; L-Methionyl-L-alanyl-L-serine methyl ester; Methyl L-methionyl-L-alanyl-L-serinate; Met-Ala-Ser-OMe; MAS-OMe; Fmoc-Met-Ala-Ser(tBu)-OH (protected precursor); Peptide Synthesis Building Block M-A-S-OMe
EINECS	Contact for details

Quality Control

Every batch of H-Met-Ala-Ser-Oh is produced and tested under strict quality management protocols. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development applications. A Certificate of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and other critical parameters is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.