Description

(1S,2R)-Cyclohexane-1,2-Dicarboxylic Acid Diethyl Ester is a high-purity chiral diester, a key synthetic intermediate prized for its defined stereochemistry. This compound is essential for the production of advanced materials and active pharmaceutical ingredients (APIs) where precise molecular geometry dictates performance. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for synthesizing enantiomerically pure drugs, particularly in cardiovascular and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides, where the specific stereoisomer can enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Specialty Polymer Modifier: Imparts specific rigidity and stereoregularity to polyesters and polyamides for high-performance engineering plastics.
• Flavor and Fragrance Ingredient: Employed in the synthesis of complex, stereospecific aroma chemicals.
• Organic Synthesis Research: A valuable reagent for methodological development in stereoselective transformations in academic and industrial R&D.

Basic Information

Product Name	(1S,2R)-Cyclohexane-1,2-Dicarboxylic Acid Diethyl Ester
CAS No.	17351-07-4
Molecular Formula	C12H20O4
Molecular Weight	228.29 g/mol
Synonyms	(1S,2R)-1,2-Cyclohexanedicarboxylic Acid Diethyl Ester; Diethyl (1S,2R)-1,2-Cyclohexanedicarboxylate; (-)-Diethyl trans-1,2-Cyclohexanedicarboxylate; (1S,2R)-Diethyl Cyclohexane-1,2-dicarboxylate; trans-(1S,2R)-Diethyl Cyclohexane-1,2-dicarboxylate; Chiral Diethyl Cyclohexane-1,2-dicarboxylate; Ethyl (1S,2R)-Cyclohexane-1,2-dicarboxylate
EINECS	Contact for details

Quality Control

Our (1S,2R)-Cyclohexane-1,2-Dicarboxylic Acid Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and GC, to ensure high enantiomeric excess (ee) and chemical purity suitable for sensitive applications. Certificates of Analysis (COA) with detailed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.