Description

Z-Pro-Phe-Oh is a protected dipeptide derivative, specifically the C-terminal carboxylic acid of the Z-protected Pro-Phe sequence. This compound serves as a crucial building block in solid-phase and solution-phase peptide synthesis, offering precise control over peptide chain assembly. It is primarily utilized by pharmaceutical R&D laboratories, biotech companies, and fine chemical manufacturers for the development of novel therapeutic peptides and biochemical probes.

Application

• Peptide Synthesis Intermediate: A key raw material for the controlled elongation of peptide chains in research and development.
• Pharmaceutical Research: Used in the discovery and synthesis of peptide-based drug candidates targeting various diseases.
• Biochemical Tool Development: Employed to create custom peptides for enzyme studies, receptor binding assays, and other biological investigations.
• Protecting Group Chemistry: The Z (benzyloxycarbonyl) group provides amine protection, allowing for selective reactions in complex molecular constructions.
• Academic Research: Serves as a standard reagent in university and institutional labs for teaching and advancing synthetic organic chemistry methodologies.
• Custom Peptide Service Providers: A fundamental component for companies offering bespoke peptide synthesis services to the global research community.

Basic Information

Product Name	Z-Pro-Phe-Oh
CAS No.	17350-17-3
Molecular Formula	C22H24N2O5
Molecular Weight	396.44 g/mol
Synonyms	N-Benzyloxycarbonyl-L-prolyl-L-phenylalanine; Z-L-Prolyl-L-phenylalanine; Z-Pro-Phe-OH; CBZ-L-Prolyl-L-phenylalanine; N-CBZ-L-Prolyl-L-phenylalanine; Nα-Carbobenzoxy-L-prolyl-L-phenylalanine; (S)-2-(((Benzyloxy)carbonyl)amino)-1-((S)-2-(phenylalanine)propanoyl)pyrrolidine-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our Z-Pro-Phe-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity, meeting the exacting standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.