Description

Z-Gly-Ala-Nh2 CAS NO 17331-79-2 is a protected dipeptide building block, specifically the benzyloxycarbonyl (Z) derivative of the glycyl-alanine amide. This compound is a critical intermediate in solid-phase peptide synthesis (SPPS), enabling the controlled elongation of peptide chains with high fidelity. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors developing novel peptide-based therapeutics, diagnostics, and biochemical tools.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex therapeutic peptides and peptidomimetics.
• Biochemical Research: Used in academic and industrial R&D for studying enzyme-substrate interactions, protein folding, and peptide structure-activity relationships (SAR).
• Solid-Phase Peptide Synthesis (SPPS): A fundamental reagent for the sequential coupling steps in both Fmoc and Boc synthesis strategies.
• Protease Inhibitor Development: Serves as a core structure or precursor in the design of inhibitors for specific proteolytic enzymes.
• Combinatorial Chemistry: Utilized in the generation of diverse peptide libraries for high-throughput screening in drug discovery.
• Custom Peptide Service: A standard reagent for contract research and manufacturing organizations (CROs/CMOs) offering bespoke peptide production.

Basic Information

Product Name	Z-Gly-Ala-Nh2
CAS No.	17331-79-2
Molecular Formula	C13H17N3O4
Molecular Weight	279.29 g/mol
Synonyms	N-Benzyloxycarbonylglycyl-L-alaninamide; Z-Gly-Ala-NH2; Cbz-Gly-Ala-NH2; Benzyl N-[(2S)-1-amino-1-oxopropan-2-yl]carbamoylmethylcarbamate; N-Carbobenzoxyglycyl-L-alaninamide; Nα-Carbobenzoxy-glycyl-L-alaninamide; Glycine, N-[(phenylmethoxy)carbonyl]-, L-alaninamide; Z-Gly-Ala-Amide
EINECS	Contact for details

Quality Control

Our Z-Gly-Ala-Nh2 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via spectroscopic methods. Certificates of Analysis (COA) with detailed batch-specific results are provided to ensure compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]D20	Specific range available on COA
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.