Description

2,2,3,3,4,4-Hexafluoro-4-Iodobutyric Acid Methyl Ester is a highly fluorinated, iodine-containing building block of significant interest in advanced organic synthesis. Its unique structure, featuring both perfluoroalkyl and iodo functionalities, makes it a versatile precursor for introducing fluorinated segments into complex molecules. This compound is particularly valuable for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to create novel compounds with tailored properties such as enhanced metabolic stability, lipophilicity, and chemical resistance.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing fluorinated active pharmaceutical ingredients (APIs) and drug candidates, leveraging fluorine's ability to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of novel fluorinated pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental persistence.
• Advanced Material Precursor: Serves as a monomer or modifier in the synthesis of specialty polymers, coatings, and liquid crystals with unique surface properties and chemical resistance.
• Organic Synthesis Reagent: Employed in cross-coupling reactions and nucleophilic substitutions to introduce perfluoroalkyl-iodo segments, enabling the construction of complex molecular architectures.
• Fluorinated Surfactant & Lubricant Research: Acts as a starting material for creating fluorinated surfactants, lubricants, and additives with exceptional thermal and chemical stability.
• Positron Emission Tomography (PET) Tracer Development: Potential use as a precursor for synthesizing fluorine-18 labeled compounds for medical imaging, given its fluorinated backbone.

Basic Information

Product Name	2,2,3,3,4,4-Hexafluoro-4-Iodobutyric Acid Methyl Ester
CAS No.	17308-98-4
Molecular Formula	C5H3F6IO2
Molecular Weight	311.97 g/mol
Synonyms	Methyl 2,2,3,3,4,4-hexafluoro-4-iodobutanoate; Methyl 4,4,4,3,3,2,2-heptafluoro-3-iodobutanoate; 4-Iodo-2,2,3,3,4,4-hexafluorobutanoic Acid Methyl Ester; Perfluoro-3-iodobutanoic Acid Methyl Ester; Heptafluoro-3-iodobutanoic Acid Methyl Ester; 3-Iodo-1,1,2,2,3,3-hexafluoropropyl Methyl Ester; Methyl α,α,β,β,γ,γ-hexafluoro-γ-iodobutyrate
EINECS	Contact for details

Quality Control

Our 2,2,3,3,4,4-Hexafluoro-4-Iodobutyric Acid Methyl Ester is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation. Certificates of Analysis (COA) detailing specific results for purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent, keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents. Ensure containers are kept upright to prevent leakage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC or HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Gravity	Contact for details
Refractive Index	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.