Description

Z-Gly-Tyr-NH2 is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of Glycyl-Tyrosine amide. This compound serves as a crucial building block in solid-phase peptide synthesis (SPPS), where it is used to introduce the Gly-Tyr sequence while protecting the amine terminus. It is primarily utilized by pharmaceutical researchers and fine chemical manufacturers involved in the development of therapeutic peptides, biochemical probes, and complex organic molecules.

Application

• Pharmaceutical Intermediate: Key raw material for the synthesis of longer, biologically active peptide sequences for drug discovery and development.
• Biochemical Research: Used as a standard or reagent in proteomics and enzymatic studies investigating peptide substrates and inhibitors.
• Solid-Phase Peptide Synthesis (SPPS): A fundamental building block for the controlled, sequential assembly of custom peptides on resin supports.
• Organic Synthesis: Serves as a chiral synthon for constructing more complex molecular architectures in medicinal chemistry.
• Reference Standard: Employed in analytical laboratories for method development and quality control of peptide-based products.

Basic Information

Product Name	Z-Gly-Tyr-NH2
CAS No.	17263-44-4
Molecular Formula	C19H21N3O5
Molecular Weight	371.39 g/mol
Synonyms	N-Benzyloxycarbonylglycyl-L-tyrosinamide; Z-Gly-Tyr-NH2; Cbz-Gly-Tyr-NH2; N-Carbobenzoxyglycyl-L-tyrosinamide; Benzyl N-[(2S)-1-amino-1-oxo-3-(4-hydroxyphenyl)propan-2-yl]carbamoylmethylcarbamate; Glycine, N-[(benzyloxy)carbonyl]-, L-tyrosinamide; Z-Gly-Tyr-Amide
EINECS	Contact for details

Quality Control

Our Z-Gly-Tyr-NH2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to ensure enantiomeric integrity, meeting the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.