Description

Z-Leu-Tyr-NH2 is a protected dipeptide derivative, specifically the C-terminal amide of the Z-protected leucine-tyrosine sequence. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), valued for its role in constructing larger, more complex peptide chains with high fidelity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of therapeutic peptides, biochemical probes, and advanced materials.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental protected amino acid derivative for the sequential assembly of custom peptide sequences.
• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in studies of enzyme-substrate interactions, receptor binding assays, and as a standard in analytical method development.
• Peptide Library Construction: Essential for generating combinatorial peptide libraries for drug discovery and screening applications.
• Conjugate Synthesis: Employed in the creation of peptide-drug conjugates or peptide-labeled compounds for targeted therapies and diagnostics.

Basic Information

Product Name	Z-Leu-Tyr-NH2
CAS No.	17263-42-2
Molecular Formula	C23H29N3O5
Molecular Weight	427.50 g/mol
Synonyms	N-Benzyloxycarbonyl-L-leucyl-L-tyrosinamide; Z-L-Leu-L-Tyr-NH2; CBZ-Leu-Tyr-NH2; Benzyloxycarbonyl-leucyl-tyrosinamide; N-Carbobenzoxy-L-leucyl-L-tyrosinamide; Leucyl-tyrosine amide, N-[(phenylmethoxy)carbonyl]-; L-Leucine, N-[(phenylmethoxy)carbonyl]-, L-tyrosinamide
EINECS	Contact for details

Quality Control

Our Z-Leu-Tyr-NH2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research and pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	-15° to -20° (c=1 in DMF)
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.