Description

N6,N6-Dimethyl-N2-Palmitoyl-L-Lysine is a synthetic, high-purity lysine derivative where the N2-amino group is acylated with palmitic acid and the N6-amino group is dimethylated. This specific chemical modification is crucial for enhancing the lipophilicity and membrane permeability of the parent amino acid, making it a valuable intermediate in advanced research and development. It is primarily sought after by pharmaceutical, cosmetic, and biochemical research sectors for its role in synthesizing novel peptide conjugates, lipidated drug candidates, and specialized surfactants.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of lipid-conjugated peptides and prodrugs to improve bioavailability and targeting.
• Cosmetic Ingredient Synthesis: Used in the development of cationic lipid compounds for hair and skin care formulations, acting as conditioning agents or emulsifiers.
• Biochemical Research: Serves as a critical reagent in studying protein lipidation, cell-penetrating peptides (CPPs), and membrane interactions.
• Surfactant & Emulsifier Development: Acts as a precursor for creating novel, mild cationic surfactants with potential applications in specialty detergents and personal care products.
• Gene Delivery Systems: Investigated as a component in the design of lipid nanoparticles (LNPs) and non-viral vectors for gene therapy applications.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	N6,N6-Dimethyl-N2-Palmitoyl-L-Lysine
CAS No.	17196-53-1
Molecular Formula	C24H48N2O3
Molecular Weight	412.65 g/mol
Synonyms	Nα-Palmitoyl-Nε,Nε-dimethyl-L-lysine; N2-Palmitoyl-N6,N6-dimethyl-L-lysine; Palmitoyl dimethyl lysine; L-Lysine, N6,N6-dimethyl-, N2-(1-oxohexadecyl)-; Lys(DiMe)-Palmitoyl; Nε,Nε-Dimethyl-Nα-palmitoyl-L-lysine
EINECS	Contact for details

Quality Control

Our N6,N6-Dimethyl-N2-Palmitoyl-L-Lysine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with every shipment to ensure full traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.