Description

5-Chloropyrimidine is a versatile halogenated heterocyclic building block essential for advanced organic synthesis. Its core value lies in its reactive chlorine atom, which facilitates efficient cross-coupling and nucleophilic substitution reactions, enabling the rapid construction of complex molecular architectures. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Used in constructing pyrimidine-based herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a precursor for functionalized ligands in catalysis and for creating novel organic electronic materials.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways and synthesizing specialized heterocyclic libraries.
• Custom Synthesis: A fundamental starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds.

Basic Information

Product Name	5-Chloropyrimidine
CAS No.	17180-94-8
Molecular Formula	C4H3ClN2
Molecular Weight	114.53 g/mol
Synonyms	5-Chloropyrimidine; Pyrimidine, 5-chloro-; 5-Chloro-1,3-diazine; NSC 5188; 17180-94-8; Chloropyrimidine; 5-Chloro-pyrimidine; 5-Chloro-1,3-diazabenzene
EINECS	241-218-7

Quality Control

Our 5-Chloropyrimidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards and can provide material suitable for research and development under current Good Manufacturing Practice (cGMP) guidelines for advanced applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.