Description

β-Chloro-D-Alanine Hydrochloride is a high-purity, non-proteinogenic amino acid derivative widely used as a key chiral building block and enzyme inhibitor in advanced research and synthesis. This compound is valued for its role in studying enzyme mechanisms and as a precursor in the development of pharmaceuticals and bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors who require high-quality, stereochemically defined intermediates for their processes.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antibiotic and enzyme-targeted drug development.
• Biochemical Research: Used as a potent, irreversible inhibitor of D-amino acid transaminase and other pyridoxal phosphate-dependent enzymes to study metabolic pathways.
• Proteomics & Enzymology: Serves as a tool compound for probing enzyme active sites and mechanisms, aiding in structural biology and drug discovery efforts.
• Agrochemical Synthesis: Employed as a building block in the research and development of chiral herbicides and plant growth regulators.
• Peptide Chemistry: Incorporated into synthetic peptides to introduce specific functionalities or to study structure-activity relationships.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation in pharmaceutical analysis.

Basic Information

Product Name	β-Chloro-D-Alanine Hydrochloride
CAS No.	17136-54-8
Molecular Formula	C3H7Cl2NO2
Molecular Weight	168.00 g/mol
Synonyms	(R)-3-Chloro-2-aminopropanoic acid hydrochloride; D-3-Chloroalanine hydrochloride; (R)-3-Chloroalanine HCl; D-β-Chloroalanine hydrochloride; (2R)-2-Amino-3-chloropropanoic acid hydrochloride; β-Chloro-D-alanine HCl; NSC 132544
EINECS	Contact for details

Quality Control

Our β-Chloro-D-Alanine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to meet the stringent requirements of research and cGMP-grade synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.