Description

2-Trifluoromethanesulfonylaniline is a high-value, multi-functional aromatic amine derivative featuring a reactive aniline group and a robust trifluoromethanesulfonyl (triflyl) moiety. This compound matters as a versatile and critical building block in advanced organic synthesis, enabling the introduction of both aniline and electron-withdrawing sulfonyl functionalities into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex intermediates, active ingredients, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those requiring sulfonamide or aniline pharmacophores for therapeutic activity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the trifluoromethanesulfonyl group enhances biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands in transition metal catalysis and organocatalysis.
• Polymer and Material Science: Incorporated into polymer backbones or as a functional modifier to impart specific chemical resistance, thermal stability, or surface properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic aromatic substitutions, and as a protected aniline derivative in multi-step synthetic routes.
• Research and Development: Essential for academic and industrial research exploring new chemical entities and reaction methodologies.

Basic Information

Product Name	2-Trifluoromethanesulfonylaniline
CAS No.	17095-18-0
Molecular Formula	C7H6F3NO2S
Molecular Weight	225.19 g/mol
Synonyms	2-Aminophenyl trifluoromethanesulfonate; 2-Triflylaniline; N-(2-Trifluoromethanesulfonyl)phenylamine; 2-(Trifluoromethanesulfonyl)aniline; 2-Aminophenyl triflate; 2-Trifluoromethanesulfonylphenylamine; o-Trifluoromethanesulfonylaniline; Benzenamine, 2-[(trifluoromethyl)sulfonyl]-
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethanesulfonylaniline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. For long-term storage, consider storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.