Description

L-Sepiapterin is a key intermediate in the biosynthesis of tetrahydrobiopterin (BH4), an essential cofactor for aromatic amino acid hydroxylases and nitric oxide synthases. This compound is crucial for research and development in metabolic pathways, neurotransmitter synthesis, and cellular redox regulation. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and manufacturers of high-purity biochemicals for applications in neuroscience, metabolic disorder studies, and enzyme research.

Application

• Biochemical Research: Essential substrate for studying the biosynthesis and recycling pathways of tetrahydrobiopterin (BH4).
• Pharmaceutical Development: Investigated as a potential therapeutic agent or precursor for conditions related to BH4 deficiency, such as certain forms of phenylketonuria (PKU) and cardiovascular diseases.
• Enzyme Activity Studies: Used in assays to measure the activity of enzymes like sepiapterin reductase.
• Neuroscience Research: Applied in studies exploring the role of BH4 in the synthesis of neurotransmitters like dopamine, serotonin, and norepinephrine.
• Cell Culture & In Vitro Models: Supplemented in media to support cellular processes dependent on adequate BH4 levels.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.

Basic Information

Product Name	L-Sepiapterin
CAS No.	17094-01-8
Molecular Formula	C9H11N5O3
Molecular Weight	237.22 g/mol
Synonyms	(6R)-2-Amino-6-[(1S,2S)-1,2-dihydroxypropyl]-5,6,7,8-tetrahydropteridin-4(3H)-one; (6R)-Sepiapterin; L-erythro-Sepiapterin; (-)-Sepiapterin; 2-Amino-6-lactoyl-7,8-dihydro-4(3H)-pteridinone; 6-Lactoyl-7,8-dihydropterin
EINECS	Contact for details

Quality Control

Our L-Sepiapterin is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-grade research standards. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability, as the compound is light-sensitive and easily oxidized. For short-term use, keep desiccated at 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.