Description

α-Ketoglutaric Acid Monosodium Salt is a key biochemical intermediate, the monosodium salt form of α-ketoglutaric acid. This compound is essential in cellular metabolism, serving as a critical substrate in the Krebs cycle and as a nitrogen scavenger in amino acid biosynthesis. It is primarily utilized by manufacturers in the pharmaceutical, nutraceutical, and research sectors for applications ranging from cell culture media supplementation to the production of diagnostic reagents and active pharmaceutical ingredients.

Application

• Pharmaceutical Intermediates: Used in the synthesis of various active pharmaceutical ingredients (APIs) and as a precursor in metabolic pathway modulation.
• Cell Culture & Fermentation Media: Serves as a vital component in mammalian and microbial cell culture media, supporting cell growth and protein production.
• Nutraceutical & Dietary Supplements: Incorporated into formulations targeting athletic performance, recovery, and metabolic health due to its role in energy production.
• Biochemical Research & Diagnostics: Employed as a standard or substrate in enzymatic assays, metabolic studies, and diagnostic kit development.
• Food & Beverage Industry: Potential use as a flavor enhancer or pH regulator in specialized food products.
• Cosmetic & Personal Care: Investigated for use in skincare products for its potential role in cellular energy and collagen synthesis.

Basic Information

Product Name	α-Ketoglutaric Acid Monosodium Salt
CAS No.	17091-15-5
Molecular Formula	C5H7NaO5
Molecular Weight	170.10 g/mol
Synonyms	Monosodium 2-Oxopentanedioate; Sodium 2-Oxoglutarate; 2-Oxoglutaric Acid Sodium Salt; AKG Sodium Salt; α-Ketoglutaric Acid Sodium Salt; Oxoglutaric Acid Sodium Salt; Sodium α-Ketoglutarate
EINECS	241-137-1

Quality Control

Our α-Ketoglutaric Acid Monosodium Salt is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, impurity profile, and residual solvent content. Our quality commitment supports applications requiring high standards, including pharmaceutical development and research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. This product is hygroscopic (moisture-sensitive) and should be kept under conditions of low humidity. Recommended long-term storage at 2-8°C. Allow the container to reach room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
pH (5% solution)	6.0 - 8.0
Loss on Drying	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Microbiological Enumeration	Meets Ph. Eur. criteria

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.