Description

Pyrido[4,3-D]Pyrimidine-2,4(1H,3H)-Dione is a heterocyclic organic compound that serves as a crucial advanced intermediate in pharmaceutical research and development. Its fused pyrido-pyrimidine-dione core structure makes it a valuable building block for synthesizing novel drug candidates, particularly in oncology and antiviral therapeutic areas. This high-purity intermediate is essential for medicinal chemists and R&D departments in pharmaceutical and biotechnology companies seeking to develop new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel small-molecule drugs targeting various disease pathways.
• Oncology Research: Used in the synthesis of potential kinase inhibitors and other anticancer agents due to its privileged scaffold.
• Antiviral Drug Development: Serves as a core structure for creating compounds with potential activity against viral enzymes.
• Medicinal Chemistry & HTS: Employed in high-throughput screening (HTS) libraries and structure-activity relationship (SAR) studies.
• Biochemical Research: Used as a reference standard or probe in enzymatic and receptor binding assays.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis services catering to pharmaceutical clients.

Basic Information

Product Name	Pyrido[4,3-D]Pyrimidine-2,4(1H,3H)-Dione
CAS No.	16952-65-1
Molecular Formula	C7H5N3O2
Molecular Weight	163.14 g/mol
Synonyms	1H-Pyrido[4,3-d]pyrimidine-2,4-dione; 2,4(1H,3H)-Pyrido[4,3-d]pyrimidinedione; 4-Hydroxy-2-oxo-1,2-dihydro-1,5-naphthyridine-3-carboxylic acid (lactam form); 1,5-Naphthyridin-4-ol, 1,2-dihydro-2-oxo-; Pyrido[4,3-d]pyrimidine-2,4(1H,3H)-dione; 16952-65-1; 1H-Pyrido[4,3-d]pyrimidine-2,4(3H)-dione
EINECS	Contact for details

Quality Control

Our Pyrido[4,3-D]Pyrimidine-2,4(1H,3H)-Dione is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.