Description

Nα-Boc-Nε-4-Toluenesulfonyl-L-Lysine Dicyclohexylammonium Salt is a high-purity, protected amino acid derivative essential for advanced peptide synthesis. This compound is specifically engineered to provide orthogonal protection for the side-chain and α-amino groups of lysine, enabling precise and sequential coupling in complex peptide assembly. It is a critical building block for researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences industries developing therapeutic peptides, peptidomimetics, and other bioactive molecules.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of lysine residues with orthogonal protecting groups.
• Solution-Phase Peptide Synthesis: Used in the synthesis of complex peptides and small proteins requiring selective deprotection strategies.
• Pharmaceutical Research: Serves as a crucial building block in the development of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the site-specific modification of peptides and proteins for drug delivery systems and diagnostic probes.
• Combinatorial Chemistry: Employed in libraries for high-throughput screening to discover new bioactive compounds.
• Academic & Industrial R&D: Fundamental reagent for studying peptide structure-activity relationships and developing new synthetic methodologies.

Basic Information

Product Name	Nα-Boc-Nε-4-Toluenesulfonyl-L-Lysine Dicyclohexylammonium Salt
CAS No.	16948-08-6
Molecular Formula	C30H51N3O6S
Molecular Weight	581.81 g/mol
Synonyms	Boc-Lys(Tos)-OH·DCHA Salt; N-α-Boc-N-ε-tosyl-L-lysine dicyclohexylammonium salt; Boc-Lys(Tos)-OH DCHA; tert-Butyloxycarbonyl-N-ε-(p-toluenesulfonyl)-L-lysine dicyclohexylamine salt; (S)-2-((tert-Butoxycarbonyl)amino)-6-((4-methylphenyl)sulfonamido)hexanoic acid dicyclohexylammonium salt; Boc-Lys(Tos)-OH · DCHA; Nalpha-Boc-Nepsilon-Tosyl-L-lysine DCHA salt
EINECS	Contact for details

Quality Control

Our Nα-Boc-Nε-4-Toluenesulfonyl-L-Lysine Dicyclohexylammonium Salt is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for sensitive peptide synthesis. Certificates of Analysis (COA) with detailed specifications are provided for each lot to guarantee traceability, consistency, and reliability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.