Description

2-(Aminomethyl)-3-Methylbutanoic Acid is a versatile chiral amino acid derivative with significant importance in organic synthesis and pharmaceutical development. Its unique structure, featuring both an amino and a carboxylic acid functional group on a branched carbon chain, makes it a valuable building block for creating complex molecules. This compound is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in peptide mimetics, active pharmaceutical ingredient (API) synthesis, and as a ligand precursor.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel APIs, particularly for neurological and metabolic disorder treatments.
• Peptidomimetic Chemistry: Used to construct non-natural amino acid residues in peptide analogs to enhance stability and bioavailability.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides and plant growth regulators.
• Ligand and Catalyst Preparation: Employed in the synthesis of chiral ligands for asymmetric catalysis and metal complexation.
• Biochemical Research: Utilized as a standard or reagent in metabolic pathway studies and enzyme inhibition assays.
• Specialty Polymer Modification: Incorporated into polymer chains to introduce functional amine groups for advanced material properties.

Basic Information

Product Name	2-(Aminomethyl)-3-Methylbutanoic Acid
CAS No.	16934-21-7
Molecular Formula	C7H15NO2
Molecular Weight	145.20 g/mol
Synonyms	3-Methyl-2-(aminomethyl)butanoic acid; L-Leucine, 3-amino- (8CI); 3-Aminomethyl-3-methylbutyric acid; 2-(Aminomethyl)-3-methylbutyric acid; β-Aminomethyl-β-methylbutyric acid; (RS)-2-(Aminomethyl)-3-methylbutanoic acid; (±)-2-(Aminomethyl)-3-methylbutanoic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(Aminomethyl)-3-Methylbutanoic Acid is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. Comprehensive analytical testing, including chiral purity assessment by HPLC, is performed to guarantee identity, potency, and purity. A detailed Certificate of Analysis (COA) documenting all test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.