Description

Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg is a synthetic peptide sequence of significant interest in biochemical and pharmaceutical research. This compound, identified by CAS NO 16875-11-9, serves as a crucial building block and model substrate for studying protease activity, enzyme kinetics, and peptide-based drug design. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical developers engaged in proteomics, biomarker discovery, and the development of novel therapeutic agents.

Application

• Biochemical Research: Used as a specific substrate for studying the activity and inhibition of various proteases, including trypsin and chymotrypsin.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the synthesis and quality control of peptide-based pharmaceuticals.
• Proteomics & Biomarker Discovery: Employed in mass spectrometry and chromatography as a calibrant or model peptide for method development and validation.
• Enzyme Kinetics Studies: Acts as a well-defined substrate to determine kinetic parameters (Km, Vmax) and elucidate enzymatic mechanisms.
• Cell Biology Research: May be used in studies investigating cell signaling pathways, receptor-ligand interactions, and peptide transport.
• Diagnostic Reagent Formulation: Incorporated into in-vitro diagnostic kits and assays for clinical testing and research purposes.

Basic Information

Product Name	Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg
CAS No.	16875-11-9
Molecular Formula	C48H66N12O11
Molecular Weight	987.1 g/mol
Synonyms	PPGFSPFR; H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; Proline-Proline-Glycine-Phenylalanine-Serine-Proline-Phenylalanine-Arginine; L-Prolyl-L-prolylglycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; Octapeptide PPGFSPFR; Trypsin Substrate Analog; Synthetic Peptide 16875-11-9
EINECS	Contact for details

Quality Control

Our Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and amino acid analysis. We provide Certificates of Analysis (COA) with detailed specifications for traceability and compliance. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.