Description

H-His-Phe-Oh CAS NO 16874-81-0 is a high-purity dipeptide derivative composed of the amino acids L-Histidine and L-Phenylalanine. This compound is a valuable building block in peptide synthesis and pharmaceutical research, offering a specific sequence for studying biological activity and developing novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical developers, and fine chemical manufacturers focused on peptide-based drug discovery and biochemical applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of more complex peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or substrate in enzymatic studies and metabolic pathway investigations.
• Peptide Library Construction: An essential component for solid-phase and solution-phase peptide synthesis to create diverse peptide libraries for screening.
• Neuroscience Research: Investigated for its potential role in neurological studies due to the presence of the histidine and phenylalanine residues.
• Cosmetic Peptide Development: Explored for potential applications in the formulation of bioactive cosmetic ingredients targeting skin health.

Basic Information

Product Name	H-His-Phe-Oh
CAS No.	16874-81-0
Molecular Formula	C15H19N5O3
Molecular Weight	317.35 g/mol
Synonyms	L-Histidyl-L-phenylalanine; Histidine-Phenylalanine; H-His-Phe-OH; L-His-L-Phe; N-(N-L-Histidyl)-L-phenylalanine; Phe-His; Phenylalanylhistidine; (S)-2-((S)-2-Amino-3-(1H-imidazol-4-yl)propanamido)-3-phenylpropanoic acid
EINECS	Contact for details

Quality Control

Our H-His-Phe-Oh is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via mass spectrometry and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccated environments.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.