Description

Z-Phe-Trp-Oh is a protected dipeptide derivative, widely recognized in the chemical and pharmaceutical industries. This compound serves as a crucial building block in peptide synthesis, offering high purity and reliability for advanced research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in academic and industrial R&D for studying enzyme-substrate interactions, receptor binding, and peptide structure-activity relationships (SAR).
• Peptide Library Construction: Essential for generating combinatorial peptide libraries used in high-throughput screening for drug discovery and diagnostic development.
• Protease Inhibitor Development: Serves as a substrate analog or precursor in the design and synthesis of specific protease inhibitors.
• Fine Chemical Synthesis: Employed as a chiral synthon in the asymmetric synthesis of more complex organic molecules and natural product analogs.

Basic Information

Product Name	Z-Phe-Trp-Oh
CAS No.	16856-28-3
Molecular Formula	C30H29N3O5
Molecular Weight	511.57 g/mol
Synonyms	N-Carbobenzoxy-L-phenylalanyl-L-tryptophan; Z-L-Phenylalanyl-L-tryptophan; Z-Phe-Trp; CBZ-Phe-Trp-OH; Nα-Cbz-L-phenylalanyl-L-tryptophan; Benzyloxycarbonylphenylalanyltryptophan; (S)-2-(((S)-1-((Benzyloxy)carbonyl)-2-phenylethyl)amino)-1-(1H-indol-3-yl)-3-oxopropane-1-carboxylic acid
EINECS	Contact for details

Quality Control

Our Z-Phe-Trp-Oh is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Specific Rotation	-20° to -25° (c=1, DMF)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.