Description

2-Methyl-L-Serine is a non-proteinogenic amino acid derivative characterized by a methyl group substitution on the β-carbon of the L-serine backbone. This structural modification makes it a valuable chiral building block and intermediate in advanced organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and industrial manufacturers in the life sciences sector for applications ranging from peptide drug development to biochemical studies.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel peptide-based therapeutics and active pharmaceutical ingredients (APIs).
• Peptide Research & Modification: Used to introduce structural diversity and study structure-activity relationships (SAR) in custom peptide sequences.
• Biochemical Probe Development: Serves as a precursor or component in the creation of probes and inhibitors for enzymatic studies.
• Agrochemical Synthesis: An intermediate in the production of specialized, high-value crop protection agents.
• Academic & Industrial R&D: Employed in chemical biology and medicinal chemistry research for discovering new bioactive compounds.

Basic Information

Product Name	2-Methyl-L-Serine
CAS No.	16820-18-1
Molecular Formula	C4H9NO3
Molecular Weight	119.12 g/mol
Synonyms	(2S)-2-Amino-2-methyl-3-hydroxypropanoic acid; L-2-Methylserine; (S)-2-Amino-2-methyl-3-hydroxypropionic acid; 2-Methyl-L-serine; β-Methyl-L-serine; L-Threonine, 3-deoxy-; L-2-Methylserine; 3-Hydroxy-2-methyl-L-alanine
EINECS	240-852-5

Quality Control

Our 2-Methyl-L-Serine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and specific test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	Contact for details
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.