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6-Chloro-7-Deazapurine-B-D-Riboside CAS NO 16754-80-6


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CAS No.:16754-80-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6-Chloro-7-Deazapurine-B-D-Riboside is a high-purity nucleoside analog and a key synthetic intermediate in medicinal chemistry. This compound matters for its critical role in the development of novel antiviral and anticancer agents, serving as a versatile building block for modified nucleosides and nucleotides. Pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers need it for advanced drug discovery programs and the synthesis of active pharmaceutical ingredients (APIs).

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies and for probing nucleic acid metabolism.
  • Antiviral Drug Development: Serves as a building block for potential therapeutics targeting viral polymerases.
  • Oncology Research: Employed in the creation of purine analogs designed to disrupt cancer cell proliferation.
  • Nucleotide Chemistry: Fundamental for synthesizing modified nucleotides for structural and functional studies.
  • Proteomics & Genomics: Can be utilized in the development of molecular probes and diagnostic tools.

Basic Information

Product Name 6-Chloro-7-Deazapurine-B-D-Riboside
CAS No. 16754-80-6
Molecular Formula C11H13ClN4O4
Molecular Weight 300.70 g/mol
Synonyms 6-Chloro-7-deazapurine riboside; 6-Chloro-7-azapurine riboside; 4-Amino-5-cyano-6-chloro-1-(β-D-ribofuranosyl)pyrrolo[2,3-d]pyrimidine; 6-Chlorotubercidin; 6-Chloro-7-deazapurine nucleoside; 6-Cl-7-DPR; 6-Chloro-7-azapurine nucleoside; 6-Chloro-1-(β-D-ribofuranosyl)-1H-pyrrolo[2,3-d]pyrimidin-4-amine
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Quality Control

Our 6-Chloro-7-Deazapurine-B-D-Riboside is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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