Description

n-α-Methyl-L-Ornithine Hydrochloride is a high-purity, non-proteinogenic amino acid derivative that serves as a critical biochemical tool and pharmaceutical intermediate. Its primary value lies in its role as a potent and selective inhibitor of nitric oxide synthase (NOS), making it essential for research into cardiovascular function, neurotransmission, and immune response pathways. This compound is particularly sought after by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers developing novel therapeutics and diagnostic agents.

Application

• Biochemical Research: As a key inhibitor (e.g., L-NMMA) in studies of the L-arginine-NO pathway, cell signaling, and enzyme kinetics.
• Pharmaceutical Development: Serves as a reference standard and a building block for synthesizing potential drug candidates targeting hypertension, septic shock, and neurodegenerative diseases.
• Diagnostic Reagent Manufacturing: Used in the formulation of assay kits and diagnostic tools for measuring nitric oxide synthase activity in biological samples.
• Academic & Clinical Studies: Employed in preclinical research to investigate the physiological and pathological roles of nitric oxide in various disease models.
• Fine Chemical Synthesis: Acts as a chiral intermediate for the synthesis of more complex, optically active molecules in medicinal chemistry.

Basic Information

Product Name	n-α-Methyl-L-Ornithine Hydrochloride
CAS No.	16748-29-1
Molecular Formula	C6H15ClN2O2
Molecular Weight	182.65 g/mol
Synonyms	L-NG-Monomethylarginine Hydrochloride; L-NMMA Hydrochloride; Nω-Methyl-L-arginine Hydrochloride; NG-Monomethyl-L-arginine hydrochloride; (S)-2-Amino-5-[(methylamino)pentanoic acid hydrochloride; Methylornithine Hydrochloride; N5-Methyl-L-ornithine hydrochloride; Nitric Oxide Synthase Inhibitor I
EINECS	240-806-8

Quality Control

Our n-α-Methyl-L-Ornithine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral purity analysis, and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.