Description

3,5-Diiodo-D-Tyrosine Hydrochloride is a halogenated derivative of the amino acid tyrosine, specifically modified with iodine atoms at the 3 and 5 positions of the aromatic ring. This compound is a critical chiral building block and intermediate in the synthesis of complex bioactive molecules, particularly in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications ranging from thyroid hormone analog studies to the development of novel radiopharmaceuticals and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of thyroid hormone analogs and other iodine-containing active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or precursor in enzymatic studies, metabolic pathway investigations, and protein labeling experiments.
• Radiopharmaceuticals: Serves as a precursor for the development of iodine-123 or iodine-131 labeled compounds used in medical imaging and therapy.
• Peptide Synthesis: Incorporated into custom peptides to study structure-activity relationships or to create novel peptide-based therapeutics.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Diagnostic Agent Development: Utilized in the research and development of contrast agents and other diagnostic tools.

Basic Information

Product Name	3,5-Diiodo-D-Tyrosine Hydrochloride
CAS No.	16711-71-0
Molecular Formula	C9H10I2NO3 • HCl
Molecular Weight	526.85 g/mol
Synonyms	D-3,5-Diiodotyrosine Hydrochloride; (2R)-2-Amino-3-(4-hydroxy-3,5-diiodophenyl)propanoic acid hydrochloride; D-DIT HCl; D-3,5-Diiodo-4-hydroxyphenylalanine hydrochloride; (R)-3-(4-Hydroxy-3,5-diiodophenyl)-2-aminopropanoic acid hydrochloride; 3,5-Diiodo-D-tyrosine HCl; D-Tyrosine, 3,5-diiodo-, hydrochloride
EINECS	240-769-8

Quality Control

Our 3,5-Diiodo-D-Tyrosine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles as determined by HPLC, NMR, and other relevant techniques.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.