Description

α-Methyl-L-Tryptophan is a non-proteinogenic amino acid derivative of L-tryptophan, characterized by a methyl group substitution at the α-carbon position. This structural modification makes it a valuable chiral building block and a key intermediate in the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for applications in drug discovery, peptide synthesis, and biochemical research.

Application

• Pharmaceutical intermediate for the synthesis of novel therapeutic agents.
• Chiral building block in asymmetric synthesis and medicinal chemistry research.
• Precursor for the development of peptide-based drugs and bioactive compounds.
• Reference standard and analytical reagent in biochemical and pharmacological studies.
• Starting material for the synthesis of specialized amino acid derivatives and unnatural amino acids.
• Research tool in metabolic pathway studies and enzyme inhibition assays.

Basic Information

Product Name	α-Methyl-L-Tryptophan
CAS No.	16709-25-4
Molecular Formula	C12H14N2O2
Molecular Weight	218.25 g/mol
Synonyms	(S)-2-Amino-3-(1H-indol-3-yl)-2-methylpropanoic acid; (S)-α-Methyltryptophan; L-α-Methyltryptophan; AMT; 1H-Indole-3-propanoic acid, α-amino-α-methyl-, (αS)-; (S)-2-Methyltryptophan; NSC 36398
EINECS	Contact for details

Quality Control

Our α-Methyl-L-Tryptophan is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results for parameters including assay, chiral purity, and related substances. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.