Description

Hexanoylcholine is a synthetic choline ester derivative, specifically the hexanoyl ester of choline. This compound is of significant interest in biochemical and pharmacological research as a model substrate for studying the activity and kinetics of cholinesterase enzymes, particularly butyrylcholinesterase. It serves as a critical tool for researchers and developers in the life sciences sector, enabling the investigation of enzyme inhibition, nerve agent detection, and potential therapeutic pathways. Key industries that utilize this specialized chemical include pharmaceutical R&D, diagnostic kit manufacturing, and academic institutions focused on neurochemistry and toxicology.

Application

• Enzymology Research: Primary substrate for in vitro assays to study the catalytic activity and inhibition profiles of butyrylcholinesterase (BChE).
• Diagnostic Development: Used in the formulation of reagent kits for clinical and environmental testing to detect cholinesterase activity levels.
• Neuropharmacology Studies: Serves as a chemical tool to investigate cholinergic signaling and the metabolism of choline esters in biological systems.
• Toxicology Screening: Employed in high-throughput screening platforms to evaluate the potency of new organophosphate and carbamate compounds.
• Biochemical Standard: Acts as a reference standard for calibrating analytical instruments like HPLC or LC-MS in method development and validation.
• Academic & Industrial R&D: Fundamental reagent for basic research and drug discovery programs targeting neurodegenerative diseases.

Basic Information

Product Name	Hexanoylcholine
CAS No.	16639-00-2
Molecular Formula	C11H24NO2+
Molecular Weight	202.31 g/mol (cation)
Synonyms	Hexanoylcholine Iodide; Choline Hexanoate Ester; N-Hexanoylcholine; 2-(Hexanoyloxy)-N,N,N-trimethylethanaminium; Hexanoylcholine Cation; Butyrylcholinesterase Substrate; BChE Substrate; Hexanoyl Choline Ester
EINECS	Contact for details

Quality Control

Our Hexanoylcholine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and diagnostic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.